Version 5.4
Bos taurus Gene: ZCCHC11
Summary
InnateDB Gene IDBG-639321.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZCCHC11
Gene Name terminal uridylyltransferase 4
Synonyms ZCCHC11
Species Bos taurus
Ensembl Gene ENSBTAG00000002721
Encoded Proteins
IDBP-691495
zinc finger, CCHC domain containing 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134744:
ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:94414997-94512804
Strand Forward strand
Band
Transcripts
ENSBTAT00000003525 ENSBTAP00000003525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
GO:0050265 RNA uridylyltransferase activity
Biological Process
GO:0001816 cytokine production
GO:0010587 miRNA catabolic process
GO:0019827 stem cell maintenance
GO:0031054 pre-miRNA processing
GO:0031123 RNA 3'-end processing
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000134744
View Gene Order
ENSMUSG00000034610
View Gene Order
Cross-References
SwissProt
TrEMBL F1MCY7
UniProt Splice Variant
Entrez Gene 528986
UniGene Bt.107263 Bt.109303 Bt.111803
RefSeq NM_001206930 XM_003582009 XM_005204560 XM_005204561 XM_005204562 XM_005204563 XM_005204564 XM_005204565 XM_005204566 XM_005204567 XM_005204568
HUGO HGNC:28981
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02008879 DAAA02008880
GenPept
RNA Seq Atlas 528986

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca