Bos taurus Gene: SEPHS2
Summary
InnateDB Gene IDBG-639367.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPHS2
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010851
Encoded Proteins
selenophosphate synthetase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179918:
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. Genes encoding selenocysteine contain a stem-loop secondary structure in their 3\' UTR called a selenocysteine insertion sequence (SECIS) element. The protein encoded by this gene contains a selenocysteine residue in its predicted active site. There is a pseudogene for this gene on chromosome 5. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:26867626-26868981
Strand Reverse strand
Band
Transcripts
ENSBTAT00000053151 ENSBTAP00000048203
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004756 selenide, water dikinase activity
GO:0005524 ATP binding
Biological Process
GO:0001887 selenium compound metabolic process
GO:0008152 metabolic process
GO:0016260 selenocysteine biosynthetic process
GO:0016310 phosphorylation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Selenocompound metabolism pathway
Selenocompound metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BHE5
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:19686
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057902
GenPept
RNA Seq Atlas