Version 5.4
Bos taurus Gene: BT.46193
Summary
InnateDB Gene IDBG-639564.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.46193
Gene Name prostasin precursor
Synonyms prostasin
Species Bos taurus
Ensembl Gene ENSBTAG00000016973
Encoded Proteins
IDBP-691736
prostasin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000052344:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:27485086-27489416
Strand Reverse strand
Band
Transcripts
ENSBTAT00000037413 ENSBTAP00000037246
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0010765 positive regulation of sodium ion transport
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000052344
View Gene Order
ENSMUSG00000030800
View Gene Order
Cross-References
SwissProt
TrEMBL F1MUB9
UniProt Splice Variant
Entrez Gene 613506
UniGene Bt.46193
RefSeq NM_001076931 XM_005224950 XM_005224951
HUGO HGNC:9491
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057919
GenPept
RNA Seq Atlas 613506

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca