Bos taurus Gene: WDR4
Summary
InnateDB Gene IDBG-639565.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR4
Gene Name tRNA (guanine-N(7)-)-methyltransferase subunit WDR4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021490
Encoded Proteins
tRNA (guanine-N(7)-)-methyltransferase subunit WDR4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160193:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:144656767-144676874
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028643 ENSBTAP00000028643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008176 tRNA (guanine-N7-)-methyltransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0036265 RNA (guanine-N7)-methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt A7E3S5
TrEMBL
UniProt Splice Variant
Entrez Gene 508051
UniGene Bt.36135
RefSeq NM_001100320 XM_005202009 XM_005202013 XM_005202014
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT030696
GenPept ABS45012
RNA Seq Atlas 508051