Bos taurus Gene: BT.64714
Summary
InnateDB Gene IDBG-639630.2
Last Modified 2013-04-25 [Report errors or provide feedback]
Gene Symbol BT.64714
Gene Name collagen alpha-1(III) chain precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021466
Encoded Proteins
collagen alpha-1(III) chain
collagen alpha-1(III) chain
Protein Structure
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168542:
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:7318227-7356937
Strand Reverse strand
Band 0
Transcripts
ENSBTAT00000028617 ENSBTAP00000028617
ENSBTAT00000038678 ENSBTAP00000038490
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005178 integrin binding
GO:0005201 extracellular matrix structural constituent
GO:0005515 protein binding
GO:0046332 SMAD binding
GO:0048407 platelet-derived growth factor binding
Biological Process
GO:0001568 blood vessel development
GO:0007160 cell-matrix adhesion
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007507 heart development
GO:0009314 response to radiation
GO:0018149 peptide cross-linking
GO:0030199 collagen fibril organization
GO:0032964 collagen biosynthetic process
GO:0034097 response to cytokine stimulus
GO:0042060 wound healing
GO:0043206 fibril organization
GO:0043588 skin development
GO:0048565 digestive tract development
GO:0050777 negative regulation of immune response
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005581 collagen
GO:0005586 collagen type III
GO:0005615 extracellular space
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Collagen biosynthesis and modifying enzymes pathway
Collagen biosynthesis and modifying enzymes pathway
KEGG
Protein digestion and absorption pathway
Amoebiasis pathway
Focal adhesion pathway
ECM-receptor interaction pathway
ECM-receptor interaction pathway
Focal adhesion pathway
Amoebiasis pathway
Protein digestion and absorption pathway
INOH
Integrin signaling pathway pathway
Integrin signaling pathway pathway
PID BIOCARTA
PID NCI
Endothelins
Beta1 integrin cell surface interactions
Cross-References
SwissProt
TrEMBL F1MXS8 F1N2Y4
UniProt Splice Variant
Entrez Gene 510833
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003919 DAAA02003920
GenPept
ImmGen BT.64714 (murine)
RNA Seq Atlas 510833
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

(Move your mouse over the image to view a more detailed version)