InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: FOXA3

Summary

InnateDB Gene

IDBG-639745.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FOXA3

Gene Name

Hepatocyte nuclear factor 3-gamma

Synonyms

HNF3-G

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012104

Encoded Proteins

IDBP-691934

Hepatocyte nuclear factor 3-gamma

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170608:
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:53834507-53841046

Strand

Forward strand

Band

Transcripts

ENSBTAT00000016056

ENSBTAP00000016056

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008134	transcription factor binding
GO:0019904	protein domain specific binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0001678	cellular glucose homeostasis
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007283	spermatogenesis
GO:0009267	cellular response to starvation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter