InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CYP4B1

Summary

InnateDB Gene

IDBG-639848.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYP4B1

Gene Name

cytochrome P450 4B1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011976

Encoded Proteins

IDBP-692051

cytochrome P450 4B1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142973:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:99937185-99957408

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000015892

ENSBTAP00000015892

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0046872	metal ion binding