Version 5.4
Bos taurus Gene: HABP2
Summary
InnateDB Gene IDBG-639873.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HABP2
Gene Name Hyaluronan-binding protein 2 Hyaluronan-binding protein 2 50 kDa heavy chain Hyaluronan-binding protein 2 50 kDa heavy chain alternate form Hyaluronan-binding protein 2 27 kDa light chain Hyaluronan-binding protein 2 27 kDa light chain alternate form
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019322
Encoded Proteins
IDBP-692073
Hyaluronan-binding protein 2Hyaluronan-binding protein 2 50 kDa heavy chainHyaluronan-binding protein 2 50 kDa heavy chain alternate formHyaluronan-binding protein 2 27 kDa light chainHyaluronan-binding protein 2 27 kDa light chain alternate form
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148702:
The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:34304685-34340148
Strand Forward strand
Band
Transcripts
ENSBTAT00000025732 ENSBTAP00000025732
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000148702
View Gene Order
ENSMUSG00000025075
View Gene Order
Cross-References
SwissProt Q5E9Z2
TrEMBL
UniProt Splice Variant
Entrez Gene 507993
UniGene Bt.16361
RefSeq NM_001014868
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105202 BT020777
GenPept AAI05203 AAX08794
RNA Seq Atlas 507993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca