InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.91072

Summary

InnateDB Gene

IDBG-639911.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.91072

Gene Name

keratin, type I cytoskeletal 14

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007583

Encoded Proteins

IDBP-692114

keratin, type I cytoskeletal 14

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186847:
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:42430195-42434559

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000036393

ENSBTAP00000036252

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:1990254	keratin filament binding

Biological Process

GO:0007568	aging
GO:0030855	epithelial cell differentiation
GO:0042633	hair cycle
GO:0045110	intermediate filament bundle assembly

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005882	intermediate filament
GO:0045095	keratin filament
GO:0070062	extracellular vesicular exosome
GO:0071944	cell periphery