Version 5.4
| Bos taurus Gene: PTCH2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-640189.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PTCH2 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000024137 | ||||||||
| Encoded Proteins |
patched 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117425:
This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:101762662-101778582 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
Hedgehog pathway
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| REACTOME |
Class B/2 (Secretin family receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR ligand binding pathway
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| KEGG |
Hedgehog signaling pathway pathway
Basal cell carcinoma pathway
Pathways in cancer pathway
Basal cell carcinoma pathway
Hedgehog signaling pathway pathway
Pathways in cancer pathway
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| INOH |
Hedgehog signaling pathway pathway
Hedgehog signaling pathway pathway
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| PID NCI |
Signaling events mediated by the Hedgehog family
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | |||||||||
| RefSeq | XM_002686431 XM_005197904 XM_005197905 XM_005197907 XM_005204892 XM_005204893 XM_005204895 XM_584648 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||