Bos taurus Gene: PLA2G12A
Summary
InnateDB Gene IDBG-640210.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLA2G12A
Gene Name group XIIA secretory phospholipase A2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015230
Encoded Proteins
group XIIA secretory phospholipase A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123739:
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:16828642-16843001
Strand Forward strand
Band
Transcripts
ENSBTAT00000020263 ENSBTAP00000020263
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005622 intracellular
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PI pathway
Acyl chain remodelling of PS pathway
Synthesis of PA pathway
Acyl chain remodelling of PG pathway
Acyl chain remodelling of PE pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PG pathway
Acyl chain remodelling of PS pathway
Acyl chain remodelling of PE pathway
Acyl chain remodelling of PI pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Synthesis of PA pathway
Phospholipid metabolism pathway
KEGG
alpha-Linolenic acid metabolism pathway
Arachidonic acid metabolism pathway
Glycerophospholipid metabolism pathway
Linoleic acid metabolism pathway
Ether lipid metabolism pathway
Vascular smooth muscle contraction pathway
Fat digestion and absorption pathway
Pancreatic secretion pathway
Glycerophospholipid metabolism pathway
Arachidonic acid metabolism pathway
Ether lipid metabolism pathway
Linoleic acid metabolism pathway
alpha-Linolenic acid metabolism pathway
Vascular smooth muscle contraction pathway
Pancreatic secretion pathway
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A5D7L0
UniProt Splice Variant
Entrez Gene 527214
UniGene Bt.22589
RefSeq NM_001098063
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140596 DAAA02016541
GenPept AAI40597
RNA Seq Atlas 527214