Version 5.4
Bos taurus Gene: BT.42611
Summary
InnateDB Gene IDBG-640292.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.42611
Gene Name ral guanine nucleotide dissociation stimulator
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004194
Encoded Proteins
IDBP-692546
ral guanine nucleotide dissociation stimulator
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160271:
Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:103126162-103139619
Strand Reverse strand
Band
Transcripts
ENSBTAT00000032653 ENSBTAP00000032582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005083 small GTPase regulator activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0050790 regulation of catalytic activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000160271
View Gene Order
ENSMUSG00000026821
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
NetPath_23
TSH pathway
REACTOME
REACT_12065
p38MAPK events pathway
REACT_12033
Signalling to RAS pathway
REACT_11061
Signalling by NGF pathway
REACT_111102
Signal Transduction pathway
REACT_12058
Signalling to ERKs pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
REACT_239722
Signalling to RAS pathway
REACT_207601
p38MAPK events pathway
REACT_231290
Signalling to ERKs pathway
REACT_248921
Signalling by NGF pathway
REACT_237883
NGF signalling via TRKA from the plasma membrane pathway
REACT_188257
Signal Transduction pathway
KEGG
hsa05210
Colorectal cancer pathway
hsa05212
Pancreatic cancer pathway
hsa05200
Pathways in cancer pathway
mmu05210
Colorectal cancer pathway
mmu05212
Pancreatic cancer pathway
mmu05200
Pathways in cancer pathway
INOH
PID NCI
erbb1_downstream_pathway
ErbB1 downstream signaling
Cross-References
SwissProt
TrEMBL F1MJY6
UniProt Splice Variant
Entrez Gene 513723
UniGene Bt.106200 Bt.42611 Bt.83162
RefSeq NM_001101978
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02032290
GenPept
RNA Seq Atlas 513723

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca