Bos taurus Gene: CCR10 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-640334.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | CCR10 | ||||||||||
Gene Name | C-C chemokine receptor type 10 | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000019095 | ||||||||||
Encoded Proteins |
Chemokine (C-C motif) receptor 10Uncharacterized protein
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184451:
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 19:43377279-43379246 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Signal Transduction pathway
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KEGG |
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
Intestinal immune network for IgA production pathway
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
Intestinal immune network for IgA production pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | B2ZSR6 D9ZDE4 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 539108 | ||||||||||
UniGene | Bt.88363 | ||||||||||
RefSeq | NM_001194964 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | DAAA02049191 EU684266 GU936965 | ||||||||||
GenPept | ACD65483 ADD82802 | ||||||||||
RNA Seq Atlas | 539108 | ||||||||||