Bos taurus Gene: TRIM56 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-640421.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | TRIM56 | ||||||||||||||
Gene Name | E3 ubiquitin-protein ligase TRIM56 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000012038 | ||||||||||||||
Encoded Proteins |
tripartite motif containing 56
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||
Summary |
[Homo sapiens] TRIM56 is a regulator of double-stranded DNA-mediated type I interferon induction where it acts as an interferon-inducible E3 ubiquitin ligase that modulates STING to confer double-stranded DNA-mediated innate immune responses.
[Homo sapiens] TRIM56 is an anti-viral host factor that restricts pestivirus infection, specifically it was found to impair bovine viral diarrhoea virus replication.
[Homo sapiens] TRIM56 is an essential component of the TLR3 anti-viral signalling pathway.
[Homo sapiens] TRIM56 was identified in a systematic screen for positive regulators of innate immune responses.
[Mus musculus] Trim56 is an anti-viral host factor that restricts pestivirus infection, specifically it was found to impair bovine viral diarrhoea virus replication.
[Mus musculus] TRIM56 is an essential component of the TLR3 anti-viral signalling pathway. (Demonstrated in human)
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Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169871:
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 25:36233862-36236129 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Innate Immune System pathway
Regulation of innate immune responses to cytosolic DNA pathway
Immune System pathway
Cytosolic sensors of pathogen-associated DNA pathway
Innate Immune System pathway
Immune System pathway
Cytosolic sensors of pathogen-associated DNA pathway
Regulation of innate immune responses to cytosolic DNA pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | |||||||||||||||
UniGene | |||||||||||||||
RefSeq | |||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | |||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | |||||||||||||||