Bos taurus Gene: CBR3
Summary
InnateDB Gene IDBG-640464.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CBR3
Gene Name carbonyl reductase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018688
Encoded Proteins
carbonyl reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159231:
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:150144149-150153934
Strand Forward strand
Band
Transcripts
ENSBTAT00000024873 ENSBTAP00000024873
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004090 carbonyl reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0070402 NADPH binding
Biological Process
GO:0008152 metabolic process
GO:0050890 cognition
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Arachidonic acid metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Arachidonic acid metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
INOH
Prostaglandin Leukotriene metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL Q0VC97
UniProt Splice Variant
Entrez Gene 516036
UniGene Bt.22496
RefSeq NM_001075734
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120284 DAAA02003565
GenPept AAI20285
RNA Seq Atlas 516036