InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.105258

Summary

InnateDB Gene

IDBG-640488.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.105258

Gene Name

primary amine oxidase, lung isozyme

Synonyms

BOLAO

Species

Bos taurus

Ensembl Gene

ENSBTAG00000030333

Encoded Proteins

IDBP-692757

primary amine oxidase, lung isozyme

IDBP-692760

primary amine oxidase, lung isozyme

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131471:
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream. [provided by RefSeq, Jul 2008]
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:43514251-43544945

Strand

Forward strand

Band

Transcripts

ENSBTAT00000042831	ENSBTAP00000040442
ENSBTAT00000052585	ENSBTAP00000047520

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005507	copper ion binding
GO:0008131	primary amine oxidase activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0048038	quinone binding