InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC17A7

Summary

InnateDB Gene

IDBG-640517.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC17A7

Gene Name

Vesicular glutamate transporter 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007036

Encoded Proteins

IDBP-692790

Vesicular glutamate transporter 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104888:
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:56343318-56354548

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000009255

ENSBTAP00000009255

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015293	symporter activity
GO:0015319	sodium:inorganic phosphate symporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0006836	neurotransmitter transport
GO:0007268	synaptic transmission
GO:0007616	long-term memory
GO:0035249	synaptic transmission, glutamatergic
GO:0035435	phosphate ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0042137	sequestering of neurotransmitter
GO:0051938	L-glutamate import
GO:0055085	transmembrane transport
GO:0060079	regulation of excitatory postsynaptic membrane potential

Cellular Component

GO:0008021	synaptic vesicle
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030672	synaptic vesicle membrane
GO:0031410	cytoplasmic vesicle
GO:0043005	neuron projection
GO:0044300	cerebellar mossy fiber
GO:0045202	synapse
GO:0048786	presynaptic active zone
GO:0060076	excitatory synapse