Version 5.4
Bos taurus Gene: FCGRT
Summary
InnateDB Gene IDBG-640575.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCGRT
Gene Name IgG receptor FcRn large subunit p51 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013926
Encoded Proteins
IDBP-692853
igG receptor FcRn large subunit p51
IDBP-692854
igG receptor FcRn large subunit p51
IDBP-692858
igG receptor FcRn large subunit p51
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104870:
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:56415700-56421861
Strand Forward strand
Band
Transcripts
ENSBTAT00000018500 ENSBTAP00000018500
ENSBTAT00000031878 ENSBTAP00000031824
ENSBTAT00000043155 ENSBTAP00000040745
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019864 IgG binding
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
GO:0038094 Fc-gamma receptor signaling pathway
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104870
View Gene Order
ENSMUSG00000003420
View Gene Order
Cross-References
SwissProt
TrEMBL Q3T119 Q866X4 Q866X5
UniProt Splice Variant
Entrez Gene 338062
UniGene Bt.1035
RefSeq XM_005219176 NM_176657 XM_005219175 XM_005219177
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY092412 AY092413 BC102159 DAAA02047478
GenPept AAI02160 AAM47495 AAM47496
RNA Seq Atlas 338062

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca