Version 5.4
Homo sapiens Gene: RNF212
Summary
InnateDB Gene IDBG-6406.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF212
Gene Name ring finger protein 212
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178222
Encoded Proteins
IDBP-6408
ring finger protein 212
IDBP-6414
ring finger protein 212
IDBP-360701
ring finger protein 212
IDBP-476046
ring finger protein 212
IDBP-483786
ring finger protein 212
IDBP-474490
ring finger protein 212
IDBP-477743
ring finger protein 212
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:1056250-1113562
Strand Reverse strand
Band p16.3
Transcripts
ENST00000382968 ENSP00000372428
ENST00000333673 ENSP00000327481
ENST00000433731 ENSP00000389709
ENST00000454487
ENST00000514024
ENST00000514757
ENST00000505693
ENST00000503206
ENST00000508633
ENST00000506730 ENSP00000425843
ENST00000511620 ENSP00000426115
ENST00000508428 ENSP00000423030
ENST00000510715 ENSP00000423560
ENST00000512552
ENST00000505730
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0006311 meiotic gene conversion
GO:0007131 reciprocal meiotic recombination
GO:0016925 protein sumoylation
GO:0051026 chiasma assembly
Cellular Component
GO:0000795 synaptonemal complex
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000055385
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001131034 NM_001193318 NM_194439 XM_005272275 XM_006713878
HUGO
OMIM
CCDS CCDS3345 CCDS46996 CCDS54704
HPRD 14158
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca