InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CENPE

Summary

InnateDB Gene

IDBG-640707.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CENPE

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009035

Encoded Proteins

IDBP-693044

centromere protein E, 312kDa

IDBP-693053

centromere protein E, 312kDa

IDBP-693070

centromere protein E, 312kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138778:
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. [provided by RefSeq, Jul 2008]
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:22959366-23041858

Strand

Forward strand

Band

Transcripts

ENSBTAT00000011898	ENSBTAP00000011898
ENSBTAT00000063749	ENSBTAP00000055956
ENSBTAT00000063831	ENSBTAP00000054962

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0043515	kinetochore binding

Biological Process

GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0045860	positive regulation of protein kinase activity
GO:0046417	chorismate metabolic process

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0000776	kinetochore
GO:0000778	condensed nuclear chromosome kinetochore
GO:0000779	condensed chromosome, centromeric region
GO:0000940	condensed chromosome outer kinetochore
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane