Bos taurus Gene: ZMPSTE24
Summary
InnateDB Gene IDBG-640812.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZMPSTE24
Gene Name CAAX prenyl protease 1 homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000044178
Encoded Proteins
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000084073:
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:106426045-106468939
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061030 ENSBTAP00000053228
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006998 nuclear envelope organization
GO:0030327 prenylated protein catabolic process
GO:0071586 CAAX-box protein processing
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Terpenoid backbone biosynthesis pathway
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BMF2
UniProt Splice Variant
Entrez Gene 538104
UniGene Bt.2472
RefSeq NM_001192928
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02009131 DAAA02009132 DAAA02009133 DAAA02009134
GenPept
RNA Seq Atlas 538104
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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