Version 5.4
Bos taurus Gene: BT.45831
Summary
InnateDB Gene IDBG-640826.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.45831
Gene Name sarcosine dehydrogenase, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004510
Encoded Proteins
IDBP-693129
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123453:
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:104578933-104634907
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005925 ENSBTAP00000005925
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004047 aminomethyltransferase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006546 glycine catabolic process
GO:0032259 methylation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000123453
View Gene Order
ENSMUSG00000009614
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00260
Glycine, serine and threonine metabolism pathway
mmu00260
Glycine, serine and threonine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BB28
UniProt Splice Variant
Entrez Gene 614603
UniGene Bt.45831
RefSeq NM_001193041 XM_005213365
HUGO HGNC:10536
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02032349 DAAA02032350
GenPept
RNA Seq Atlas 101910169 614603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca