Version 5.4
| Bos taurus Gene: G6PC2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-641024.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | G6PC2 | ||||||||
| Gene Name | glucose-6-phosphatase 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000004241 | ||||||||
| Encoded Proteins |
glucose-6-phosphatase, catalytic, 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152254:
This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 2:27274585-27281293 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Glucose transport pathway
Hexose transport pathway
Transmembrane transport of small molecules pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
Disease pathway
Glycogen storage diseases pathway
Disease pathway
SLC-mediated transmembrane transport pathway
Metabolism pathway
Glucose transport pathway
Transmembrane transport of small molecules pathway
Hexose transport pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
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| KEGG |
Galactose metabolism pathway
Glycolysis / Gluconeogenesis pathway
Insulin signaling pathway pathway
Starch and sucrose metabolism pathway
Adipocytokine signaling pathway pathway
Carbohydrate digestion and absorption pathway
Insulin signaling pathway pathway
Glycolysis / Gluconeogenesis pathway
Starch and sucrose metabolism pathway
Galactose metabolism pathway
Adipocytokine signaling pathway pathway
Carbohydrate digestion and absorption pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1MSR0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 505012 | ||||||||
| UniGene | Bt.106480 | ||||||||
| RefSeq | NM_001192046 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02004289 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 505012 | ||||||||