Version 5.4
Bos taurus Gene: DAGLB
Summary
InnateDB Gene IDBG-641025.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DAGLB
Gene Name sn1-specific diacylglycerol lipase beta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009236
Encoded Proteins
IDBP-693343
sn1-specific diacylglycerol lipase beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23103940
[Mus musculus] DAGLB is a key metabolic hub within a lipid network that regulates proinflammatory responses in peritoneal macrophages.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164535:
Gene Information
Type Protein coding
Genomic Location Chromosome 25:38842844-38866581
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012173 ENSBTAP00000012173
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004806 triglyceride lipase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0007405 neuroblast proliferation
GO:0019369 arachidonic acid metabolic process
GO:0022008 neurogenesis
GO:0042136 neurotransmitter biosynthetic process
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164535
View Gene Order
ENSMUSG00000039206
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19308
Arachidonate production from DAG pathway
REACT_2202
Effects of PIP2 hydrolysis pathway
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14797
Signaling by GPCR pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_604
Hemostasis pathway
REACT_223625
GPCR downstream signaling pathway
REACT_224553
Hemostasis pathway
REACT_254215
Signaling by GPCR pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_247231
Arachidonate production from DAG pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_219232
Effects of PIP2 hydrolysis pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A3KMV4
UniProt Splice Variant
Entrez Gene 538021
UniGene Bt.1489
RefSeq NM_001083487
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133292 DAAA02058341
GenPept AAI33293
RNA Seq Atlas 538021

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca