Bos taurus Gene: CDH4 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-641044.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | CDH4 | ||||||||||
Gene Name | Uncharacterized protein | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000015058 | ||||||||||
Encoded Proteins |
cadherin 4, type 1, R-cadherin (retinal)
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179242:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 13:55672235-55803649 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Adherens junctions interactions pathway
CDO in myogenesis pathway
Developmental Biology pathway
Cell-Cell communication pathway
Cell junction organization pathway
Myogenesis pathway
Cell-cell junction organization pathway
Cell-cell junction organization pathway
Adherens junctions interactions pathway
Cell junction organization pathway
Cell-Cell communication pathway
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KEGG |
Cell adhesion molecules (CAMs) pathway
Cell adhesion molecules (CAMs) pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | F1MW29 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 525796 | ||||||||||
UniGene | Bt.61960 | ||||||||||
RefSeq | XM_002692260 XM_005194394 XM_005214933 XM_604152 | ||||||||||
HUGO | HGNC:1763 | ||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | DAAA02036267 DAAA02036268 DAAA02036269 DAAA02036270 DAAA02036271 DAAA02036272 DAAA02036273 | ||||||||||
GenPept | |||||||||||
RNA Seq Atlas | 525796 | ||||||||||