Bos taurus Gene: BT.88362
Summary
InnateDB Gene IDBG-641056.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.88362
Gene Name glycylpeptide N-tetradecanoyltransferase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006051
Encoded Proteins
glycylpeptide N-tetradecanoyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136448:
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:45375505-45406315
Strand Forward strand
Band
Transcripts
ENSBTAT00000007950 ENSBTAP00000007950
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0001701 in utero embryonic development
GO:0006499 N-terminal protein myristoylation
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Activation, myristolyation of BID and translocation to mitochondria pathway
Late Phase of HIV Life Cycle pathway
Apoptosis pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
HIV Life Cycle pathway
Visual phototransduction pathway
HIV Infection pathway
The phototransduction cascade pathway
Intrinsic Pathway for Apoptosis pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
Disease pathway
Apoptosis pathway
Disease pathway
Activation, myristolyation of BID and translocation to mitochondria pathway
Visual phototransduction pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
The phototransduction cascade pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Intrinsic Pathway for Apoptosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.88362
RefSeq NM_177504
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas