Bos taurus Gene: CTSZ
Summary
InnateDB Gene IDBG-641151.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTSZ
Gene Name cathepsin Z precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018784
Encoded Proteins
cathepsin Z precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101160:
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:57889707-57899205
Strand Forward strand
Band
Transcripts
ENSBTAT00000025007 ENSBTAP00000025007
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0060441 epithelial tube branching involved in lung morphogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of Angiotensinogen to Angiotensins pathway
Lysosome Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Metabolism of proteins pathway
Peptide hormone metabolism pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Lysosome Vesicle Biogenesis pathway
Metabolism of proteins pathway
Peptide hormone metabolism pathway
Metabolism of Angiotensinogen to Angiotensins pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
KEGG
Lysosome pathway
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MW68
UniProt Splice Variant
Entrez Gene 404187
UniGene Bt.4902
RefSeq NM_001077835
HUGO HGNC:2547
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036315
GenPept
RNA Seq Atlas 404187