Version 5.4
Bos taurus Gene: LIM2
Summary
InnateDB Gene IDBG-641357.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIM2
Gene Name Lens fiber membrane intrinsic protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003231
Encoded Proteins
IDBP-693715
Lens fiber membrane intrinsic protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105370:
This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:57819483-57826637
Strand Reverse strand
Band
Transcripts
ENSBTAT00000004191 ENSBTAP00000004191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005212 structural constituent of eye lens
Biological Process
GO:0002088 lens development in camera-type eye
GO:0043010 camera-type eye development
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105370
View Gene Order
ENSMUSG00000004613
View Gene Order
Cross-References
SwissProt P20274
TrEMBL
UniProt Splice Variant
Entrez Gene 281282
UniGene Bt.431
RefSeq NM_174102
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL L04188
GenPept AAA30621
RNA Seq Atlas 281282

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca