Version 5.4
Bos taurus Gene: TAF1D
Summary
InnateDB Gene IDBG-641644.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAF1D
Gene Name TATA box-binding protein-associated factor RNA polymerase I subunit D
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003545
Encoded Proteins
IDBP-694025
TATA box-binding protein-associated factor RNA polymerase I subunit D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166012:
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:1056627-1062580
Strand Forward strand
Band
Transcripts
ENSBTAT00000004611 ENSBTAP00000004611
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005668 RNA polymerase transcription factor SL1 complex
GO:0005815 microtubule organizing center
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000166012
View Gene Order
ENSMUSG00000031939
View Gene Order
Pathways
NETPATH
REACTOME
REACT_221445
RNA Polymerase I Transcription Termination pathway
REACT_217942
SIRT1 negatively regulates rRNA Expression pathway
REACT_213048
Epigenetic regulation of gene expression pathway
REACT_203707
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_217354
RNA Polymerase I Promoter Escape pathway
REACT_207088
RNA Polymerase I Transcription pathway
REACT_226022
Gene Expression pathway
REACT_225163
RNA Polymerase I Chain Elongation pathway
REACT_208197
RNA Polymerase I Transcription Initiation pathway
REACT_215001
Negative epigenetic regulation of rRNA expression pathway
REACT_219488
RNA Polymerase I Promoter Clearance pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1074
RNA Polymerase I Transcription Termination pathway
REACT_2204
RNA Polymerase I Chain Elongation pathway
REACT_1913
RNA Polymerase I Promoter Escape pathway
REACT_953
RNA Polymerase I Transcription Initiation pathway
REACT_1309
RNA Polymerase I Transcription pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_1974
RNA Polymerase I Promoter Clearance pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_200827
SIRT1 negatively regulates rRNA Expression pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
REACT_245058
RNA Polymerase I Transcription pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_257165
RNA Polymerase I Transcription Termination pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_224328
SIRT1 negatively regulates rRNA Expression pathway
REACT_233572
Gene Expression pathway
REACT_207809
Negative epigenetic regulation of rRNA expression pathway
REACT_232235
RNA Polymerase I Promoter Escape pathway
REACT_240511
RNA Polymerase I Promoter Clearance pathway
REACT_259097
RNA Polymerase I Chain Elongation pathway
REACT_235780
RNA Polymerase I Transcription Initiation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q32LB6
TrEMBL
UniProt Splice Variant
Entrez Gene 505533
UniGene Bt.109490
RefSeq NM_001037586
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109659
GenPept AAI09660
RNA Seq Atlas 505533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca