Bos taurus Gene: SUV420H2
Summary
InnateDB Gene IDBG-641830.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUV420H2
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014087
Encoded Proteins
suppressor of variegation 4-20 homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133247:
SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:62580694-62587280
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018728 ENSBTAP00000018728
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042799 histone methyltransferase activity (H4-K20 specific)
GO:0046982 protein heterodimerization activity
Biological Process
GO:0016571 histone methylation
GO:0034770 histone H4-K20 methylation
GO:0034773 histone H4-K20 trimethylation
Cellular Component
GO:0000780 condensed nuclear chromosome, centromeric region
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Lysine degradation pathway
Lysine degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B8M1
UniProt Splice Variant
Entrez Gene 519777
UniGene Bt.111378
RefSeq XM_002695387 XM_598002
HUGO HGNC:28405
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047747
GenPept
RNA Seq Atlas 519777