Version 5.4
Bos taurus Gene: SYT5
Summary
InnateDB Gene IDBG-641913.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYT5
Gene Name synaptotagmin-5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002522
Encoded Proteins
IDBP-694321
synaptotagmin-5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129990:
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:62700854-62707444
Strand Forward strand
Band
Transcripts
ENSBTAT00000003272 ENSBTAP00000003272
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006810 transport
GO:0017156 calcium ion-dependent exocytosis
Cellular Component
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0031045 dense core granule
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000129990
View Gene Order
ENSMUSG00000004961
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18325
Regulation of insulin secretion pathway
REACT_1505
Integration of energy metabolism pathway
REACT_111217
Metabolism pathway
REACT_217323
Integration of energy metabolism pathway
REACT_188937
Metabolism pathway
REACT_263148
Regulation of insulin secretion pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A4IFJ2 B1GVY5
UniProt Splice Variant
Entrez Gene 539616
UniGene Bt.91710
RefSeq NM_001083744 XM_005219706
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AM930544 BC134606 DAAA02047752
GenPept AAI34607 CAP59625
RNA Seq Atlas 539616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca