Version 5.4
Bos taurus Gene: FN3KRP
Summary
InnateDB Gene IDBG-642013.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FN3KRP
Gene Name ketosamine-3-kinase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015390
Encoded Proteins
IDBP-694425
ketosamine-3-kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141560:
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:50555062-50562978
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020456 ENSBTAP00000020456
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0016310 phosphorylation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000141560
View Gene Order
ENSMUSG00000039253
View Gene Order
Cross-References
SwissProt
TrEMBL Q0P592
UniProt Splice Variant
Entrez Gene 615868
UniGene Bt.30570
RefSeq NM_001076399 XM_005221061 XM_005221062
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120335 DAAA02049365
GenPept AAI20336
RNA Seq Atlas 615868

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca