Bos taurus Gene: TEC | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-642096.3 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | TEC | ||||||||||||||||||||
Gene Name | Uncharacterized protein | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000005062 | ||||||||||||||||||||
Encoded Proteins |
tec protein tyrosine kinase
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135605:
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 6:68468930-68530673 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH |
KitReceptor pathway
TCR pathway
BCR pathway
IL3 pathway
IL6 pathway
TSLP pathway
Prolactin pathway
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REACTOME |
Interleukin-3, 5 and GM-CSF signaling pathway
Signaling by SCF-KIT pathway
Cytokine Signaling in Immune system pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
Immune System pathway
Signaling by Interleukins pathway
FCERI mediated Ca+2 mobilization pathway
Innate Immune System pathway
Signaling by SCF-KIT pathway
Cytokine Signaling in Immune system pathway
Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
FCERI mediated Ca+2 mobilization pathway
Signaling by Interleukins pathway
Interleukin-3, 5 and GM-CSF signaling pathway
Signal Transduction pathway
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KEGG |
T cell receptor signaling pathway pathway
Osteoclast differentiation pathway
T cell receptor signaling pathway pathway
Osteoclast differentiation pathway
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INOH |
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
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PID NCI |
EPO signaling pathway
Signaling events mediated by Stem cell factor receptor (c-Kit)
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Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
UniGene | Bt.42869 | ||||||||||||||||||||
RefSeq | XM_002688249 XM_005207975 XM_005207976 XM_005207977 XM_580898 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | |||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||