Version 5.4
| Bos taurus Gene: SLC16A3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-642156.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SLC16A3 | ||||||||
| Gene Name | monocarboxylate transporter 4 | ||||||||
| Synonyms | MCT4 | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000017461 | ||||||||
| Encoded Proteins |
monocarboxylate transporter 4
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141526:
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 19:51243972-51255385 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Basigin interactions pathway
Cell surface interactions at the vascular wall pathway
Proton-coupled monocarboxylate transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Pyruvate metabolism pathway
Transmembrane transport of small molecules pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
Hemostasis pathway
Hemostasis pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Cell surface interactions at the vascular wall pathway
Metabolism pathway
Basigin interactions pathway
Pyruvate metabolism pathway
Proton-coupled monocarboxylate transport pathway
Transmembrane transport of small molecules pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | B2DG18 F1MXZ2 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 510085 | ||||||||
| UniGene | Bt.48774 | ||||||||
| RefSeq | NM_001109980 XM_005221025 XM_005221026 XM_005221027 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB435503 DAAA02049398 | ||||||||
| GenPept | BAG31380 | ||||||||
| RNA Seq Atlas | 510085 | ||||||||