InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CEP250

Summary

InnateDB Gene

IDBG-642166.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CEP250

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006021

Encoded Proteins

IDBP-694598

centrosomal protein 250kDa

IDBP-694602

centrosomal protein 250kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126001:
This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. [provided by RefSeq, Jun 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:65366076-65405852

Strand

Forward strand

Band

Transcripts

ENSBTAT00000007911	ENSBTAP00000007911
ENSBTAT00000063863	ENSBTAP00000056531

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0019901	protein kinase binding
GO:0019904	protein domain specific binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0008104	protein localization
GO:0010457	centriole-centriole cohesion
GO:0030997	regulation of centriole-centriole cohesion
GO:0033365	protein localization to organelle