Bos taurus Gene: PARVB | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-642203.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | PARVB | ||||||||||
Gene Name | beta-parvin | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000021978 | ||||||||||
Encoded Proteins |
beta-parvin
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188677:
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 5:115517820-115572329 | ||||||||||
Strand | Forward strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components pathway
Cell-extracellular matrix interactions pathway
Cell-Cell communication pathway
Cell junction organization pathway
Cell-extracellular matrix interactions pathway
Cell junction organization pathway
Cell-Cell communication pathway
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components pathway
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KEGG |
Focal adhesion pathway
Focal adhesion pathway
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INOH | |||||||||||
PID NCI |
Integrin-linked kinase signaling
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Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | A6QLQ6 F1MC75 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 616294 | ||||||||||
UniGene | Bt.45371 | ||||||||||
RefSeq | NM_001102299 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | BC148050 DAAA02014885 DAAA02014886 DAAA02014887 DAAA02014888 DAAA02014889 | ||||||||||
GenPept | AAI48051 | ||||||||||
RNA Seq Atlas | 616294 | ||||||||||