InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: HDAC10

Summary

InnateDB Gene

IDBG-642517.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HDAC10

Gene Name

histone deacetylase 10

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011000

Encoded Proteins

IDBP-694983

histone deacetylase 10

IDBP-694986

histone deacetylase 10

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100429:
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:119814028-119819426

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000014602	ENSBTAP00000014602
ENSBTAT00000042583	ENSBTAP00000040218

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004407	histone deacetylase activity
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0019899	enzyme binding
GO:0033558	protein deacetylase activity
GO:0042826	histone deacetylase binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0006476	protein deacetylation
GO:0008152	metabolic process
GO:0016575	histone deacetylation
GO:0045892	negative regulation of transcription, DNA-templated