InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TECR

Summary

InnateDB Gene

IDBG-642665.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TECR

Gene Name

Trans-2,3-enoyl-CoA reductase

Synonyms

GPSN2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012632

Encoded Proteins

IDBP-695145

Trans-2,3-enoyl-CoA reductase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099797:
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:12329820-12357348

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000036271

ENSBTAP00000036133

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

Biological Process

GO:0006629	lipid metabolic process
GO:0006694	steroid biosynthetic process
GO:0030497	fatty acid elongation
GO:0042761	very long-chain fatty acid biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030176	integral component of endoplasmic reticulum membrane