Version 5.4
Bos taurus Protein: TECR
Summary
InnateDB Protein IDBP-695145.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TECR
Protein Name Trans-2,3-enoyl-CoA reductase
Synonyms GPSN2;
Species Bos taurus
Ensembl Protein ENSBTAP00000036133
InnateDB Gene IDBG-642665 (TECR)
Protein Structure
UniProt Annotation
Function Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
Biological Process
GO:0006629 lipid metabolic process
GO:0006694 steroid biosynthetic process
GO:0030497 fatty acid elongation
GO:0042761 very long-chain fatty acid biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
IPR029071 Ubiquitin-related domain
PFAM PF02544
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3ZCD7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614105
UniGene
RefSeq NP_001029920
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102503
GenPept AAI02504

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca