Bos taurus Gene: BT.37042
Summary
InnateDB Gene IDBG-642676.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.37042
Gene Name ubiquitin-like modifier-activating enzyme 6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006837
Encoded Proteins
ubiquitin-like modifier-activating enzyme 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000033178:
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:85050210-85137078
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008985 ENSBTAP00000008985
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008641 small protein activating enzyme activity
GO:0019780 FAT10 activating enzyme activity
Biological Process
GO:0006464 cellular protein modification process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0032446 protein modification by small protein conjugation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
Class I MHC mediated antigen processing & presentation pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
KEGG
Ubiquitin mediated proteolysis pathway
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1ME38
UniProt Splice Variant
Entrez Gene 518834
UniGene Bt.37042
RefSeq NM_001083438
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02017977 DAAA02017978
GenPept
RNA Seq Atlas 518834