Version 5.4
Bos taurus Gene: LGALS3BP
Summary
InnateDB Gene IDBG-642788.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS3BP
Gene Name Galectin-3-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001368
Encoded Proteins
IDBP-695284
Galectin-3-binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108679:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:54035259-54045168
Strand Forward strand
Band
Transcripts
ENSBTAT00000001802 ENSBTAP00000001802
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
Predicted by orthology
Total 39 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007155 cell adhesion
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0016020 membrane
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000108679
View Gene Order
ENSMUSG00000033880
View Gene Order
Cross-References
SwissProt A7E3W2
TrEMBL
UniProt Splice Variant
Entrez Gene 531137
UniGene Bt.6597
RefSeq NM_001046316 XM_005221235 XM_005221236
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105367 BT030733
GenPept AAI05368 ABS45049
RNA Seq Atlas 531137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca