Version 5.4
Bos taurus Gene: WBP2
Summary
InnateDB Gene IDBG-643135.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WBP2
Gene Name WW domain-binding protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008634
Encoded Proteins
IDBP-695676
WW domain binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132471:
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56394188-56401350
Strand Forward strand
Band
Transcripts
ENSBTAT00000011385 ENSBTAP00000011385
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0001105 RNA polymerase II transcription coactivator activity
GO:0005515 protein binding
GO:0031490 chromatin DNA binding
Biological Process
GO:0045184 establishment of protein localization
GO:0045815 positive regulation of gene expression, epigenetic
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0071391 cellular response to estrogen stimulus
GO:0071442 positive regulation of histone H3-K14 acetylation
Cellular Component
GO:0000790 nuclear chromatin
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132471
View Gene Order
ENSMUSG00000034341
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BGX4
UniProt Splice Variant
Entrez Gene 507060
UniGene Bt.7944
RefSeq NM_001192132
HUGO HGNC:12738
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049511
GenPept
RNA Seq Atlas 507060

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca