Version 5.4
| Bos taurus Gene: ICAM4 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-643255.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ICAM4 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000010314 | ||||||||
| Encoded Proteins |
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105371:
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:16051851-16052907 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Integrin cell surface interactions pathway
Extracellular matrix organization pathway
Adaptive Immune System pathway
Immune System pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Immune System pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
Adaptive Immune System pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Beta2 integrin cell surface interactions
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1B762 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 514873 | ||||||||
| UniGene | Bt.61530 | ||||||||
| RefSeq | XM_002688841 XM_592787 | ||||||||
| HUGO | HGNC:5347 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02019454 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 514873 | ||||||||