Bos taurus Gene: ATG4D
Summary
InnateDB Gene IDBG-643294.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATG4D
Gene Name cysteine protease ATG4D
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010727
Encoded Proteins
cysteine protease ATG4D
cysteine protease ATG4D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130734:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:16279903-16288392
Strand Forward strand
Band
Transcripts
ENSBTAT00000014200 ENSBTAP00000014200
ENSBTAT00000053355 ENSBTAP00000052669
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006810 transport
GO:0006914 autophagy
GO:0015031 protein transport
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Regulation of autophagy pathway
Regulation of autophagy pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N5L1
UniProt Splice Variant
Entrez Gene 615657
UniGene Bt.30691
RefSeq NM_001099146
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019466
GenPept
RNA Seq Atlas 615657