Version 5.4
Bos taurus Gene: BT.21158
Summary
InnateDB Gene IDBG-643306.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.21158
Gene Name ADP-ribosylation factor-binding protein GGA3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016128
Encoded Proteins
IDBP-695863
ADP-ribosylation factor-binding protein GGA3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125447:
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56863207-56877029
Strand Forward strand
Band
Transcripts
ENSBTAT00000056864 ENSBTAP00000049152
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030306 ADP-ribosylation factor binding
Biological Process
GO:0006886 intracellular protein transport
GO:0045732 positive regulation of protein catabolic process
Cellular Component
GO:0005622 intracellular
GO:0005802 trans-Golgi network
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000125447
View Gene Order
ENSMUSG00000020740
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04142
Lysosome pathway
mmu04142
Lysosome pathway
INOH
PID NCI
arf_3pathway
Arf1 pathway
Cross-References
SwissProt
TrEMBL G5E690
UniProt Splice Variant
Entrez Gene 510539
UniGene Bt.21158
RefSeq NM_001083404 XM_005221179 XM_005221180 XM_005221181
HUGO HGNC:17079
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049525
GenPept
RNA Seq Atlas 510539

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca