Mus musculus Gene: Gga3
Summary
InnateDB Gene IDBG-214327.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gga3
Gene Name golgi associated, gamma adaptin ear containing, ARF binding protein 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020740
Encoded Proteins
golgi associated, gamma adaptin ear containing, ARF binding protein 3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125447:
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:115584255-115604051
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000019135 ENSMUSP00000019135
ENSMUST00000106508 ENSMUSP00000102117
ENSMUST00000156173 ENSMUSP00000138597
ENSMUST00000154832
ENSMUST00000123485
ENSMUST00000128437
ENSMUST00000136790
ENSMUST00000123831
ENSMUST00000148782
ENSMUST00000125097 ENSMUSP00000118024
ENSMUST00000149814
ENSMUST00000132503
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030306 ADP-ribosylation factor binding
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0045732 positive regulation of protein catabolic process
Cellular Component
GO:0005622 intracellular
GO:0005802 trans-Golgi network
GO:0010008 endosome membrane
GO:0030131 clathrin adaptor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Lysosome pathway
INOH
PID NCI
Arf1 pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.119479
RefSeq NM_001252067 NM_173048 XM_006533365 XM_006533366
OMIM
CCDS CCDS25641 CCDS56817
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas