Version 5.4
Bos taurus Gene: ADAM23
Summary
InnateDB Gene IDBG-643424.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM23
Gene Name disintegrin and metalloproteinase domain-containing protein 23
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019694
Encoded Proteins
IDBP-695984
disintegrin and metalloproteinase domain-containing protein 23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114948:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. [provided by RefSeq, Jul 2008]
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:95145119-95340402
Strand Forward strand
Band
Transcripts
ENSBTAT00000026254 ENSBTAP00000026254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000114948
View Gene Order
ENSMUSG00000025964
View Gene Order
Cross-References
SwissProt
TrEMBL A4FUX7
UniProt Splice Variant
Entrez Gene 531241
UniGene Bt.55468 Bt.75718
RefSeq NM_001083458 XM_005202734
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123411 DAAA02005684
GenPept AAI23412
RNA Seq Atlas 531241

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca