Version 5.4
Bos taurus Gene: ROM1
Summary
InnateDB Gene IDBG-643595.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ROM1
Gene Name Rod outer segment membrane protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001188
Encoded Proteins
IDBP-696155
Rod outer segment membrane protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149489:
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:41655047-41657047
Strand Forward strand
Band
Transcripts
ENSBTAT00000001574 ENSBTAP00000001574
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007601 visual perception
GO:0010468 regulation of gene expression
GO:0060042 retina morphogenesis in camera-type eye
GO:0060219 camera-type eye photoreceptor cell differentiation
GO:0061298 retina vasculature development in camera-type eye
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042622 photoreceptor outer segment membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000149489
View Gene Order
ENSMUSG00000071648
View Gene Order
Cross-References
SwissProt P52205
TrEMBL
UniProt Splice Variant
Entrez Gene 281465
UniGene Bt.558
RefSeq NM_174174
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118152 D83385 U72027
GenPept AAB17187 AAI18153 BAA11900
RNA Seq Atlas 281465

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca