InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.19318

Summary

InnateDB Gene

IDBG-643600.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.19318

Gene Name

long-chain specific acyl-CoA dehydrogenase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000010579

Encoded Proteins

IDBP-696165

long-chain specific acyl-CoA dehydrogenase, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115361:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:98416824-98456944

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000013988

ENSBTAP00000013988

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003995	acyl-CoA dehydrogenase activity
GO:0004466	long-chain-acyl-CoA dehydrogenase activity
GO:0016401	palmitoyl-CoA oxidase activity
GO:0016491	oxidoreductase activity
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0001659	temperature homeostasis
GO:0008152	metabolic process
GO:0019254	carnitine metabolic process, CoA-linked
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042413	carnitine catabolic process
GO:0044242	cellular lipid catabolic process
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0046322	negative regulation of fatty acid oxidation
GO:0055114	oxidation-reduction process
GO:0090181	regulation of cholesterol metabolic process