Bos taurus Gene: POLR2G
Summary
InnateDB Gene IDBG-643671.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR2G
Gene Name DNA-directed RNA polymerase II subunit RPB7
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009483
Encoded Proteins
DNA-directed RNA polymerase II subunit RPB7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168002:
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:41777028-41780288
Strand Forward strand
Band
Transcripts
ENSBTAT00000012481 ENSBTAP00000012481
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
Predicted by orthology
Total 39 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0003727 single-stranded RNA binding
GO:0003899 DNA-directed RNA polymerase activity
GO:0031369 translation initiation factor binding
Biological Process
GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0006351 transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0045948 positive regulation of translational initiation
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005665 DNA-directed RNA polymerase II, core complex
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
RNA Polymerase II Transcription pathway
mRNA Capping pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
Transcription-coupled NER (TC-NER) pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
Gene Expression pathway
Nucleotide Excision Repair pathway
Transcriptional regulation by small RNAs pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
RNA Polymerase II Transcription Elongation pathway
DNA Repair pathway
Dual incision reaction in TC-NER pathway
Formation of RNA Pol II elongation complex pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
mRNA Splicing - Minor Pathway pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Polymerase II Transcription Initiation pathway
Regulatory RNA pathways pathway
Formation of the Early Elongation Complex pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Tat-mediated HIV elongation arrest and recovery pathway
Pausing and recovery of Tat-mediated HIV elongation pathway
Viral Messenger RNA Synthesis pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Capping pathway
MicroRNA (miRNA) biogenesis pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
Formation of RNA Pol II elongation complex pathway
Formation of the Early Elongation Complex pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
Formation of HIV elongation complex in the absence of HIV Tat pathway
HIV Transcription Initiation pathway
Pausing and recovery of HIV elongation pathway
RNA Polymerase II HIV Promoter Escape pathway
Formation of the HIV-1 Early Elongation Complex pathway
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
Tat-mediated elongation of the HIV-1 transcript pathway
Abortive elongation of HIV-1 transcript in the absence of Tat pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
HIV elongation arrest and recovery pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
Dual incision reaction in TC-NER pathway
Transcription-coupled NER (TC-NER) pathway
Influenza Infection pathway
Transcriptional regulation by small RNAs pathway
Influenza Viral RNA Transcription and Replication pathway
HIV Transcription Elongation pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
HIV Infection pathway
Influenza Life Cycle pathway
mRNA Splicing pathway
Nucleotide Excision Repair pathway
Gene Expression pathway
Disease pathway
DNA Repair pathway
Regulatory RNA pathways pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
Transcription-coupled NER (TC-NER) pathway
Formation of the Early Elongation Complex pathway
mRNA Splicing pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
RNA Polymerase II Transcription Initiation pathway
mRNA Splicing - Minor Pathway pathway
RNA Polymerase II Promoter Escape pathway
Nucleotide Excision Repair pathway
Formation of RNA Pol II elongation complex pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
DNA Repair pathway
Transcriptional regulation by small RNAs pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Pre-transcription Events pathway
mRNA Capping pathway
Gene Expression pathway
Regulatory RNA pathways pathway
mRNA Splicing - Major Pathway pathway
Dual incision reaction in TC-NER pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
KEGG
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Huntington's disease pathway
Pyrimidine metabolism pathway
RNA polymerase pathway
Purine metabolism pathway
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001015633
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas